Key model of drug development for complications of diabetes
Diabetic complications are various complications that may occur after having diabetes for a long period of time, including cardiovascular disease, neuropathy, eye disease, kidney disease and so on. Diabetic patients can damage various tissues and organs due to long-term instability of blood sugar, leading to complications. Therefore, prevention and early treatment of diabetic complications are very important.We have established stable models of diabetic complications such as kidney, skin, and foot, which are suitable for the research of drugs for preclinical diabetic complications and the evaluation of new drugs.
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Disease name | Model name | Animal species |
Complications of diabetes | Type II diabetes nephropathy model induced by high-fat diet+streptozotocin (STZ) | mouse |
Type II diabetes nephropathy model in db/db mice | mouse | |
Streptozotocin (STZ) induced peripheral vascular disease model of type I diabetes | rat | |
Cataract model of type I diabetes induced by streptozotocin (STZ) | rat |
Case sharing
SD rat model of type I diabetes PAD+foot ulcer
Model of skin defect healing in type 2 diabetes
