Key Model for Drug Development of Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune disease that is pathologically based on synovitis and may eventually lead to joint deformities. Although there is no complete cure for the disease for the time being, early disease control and maintenance therapy can effectively slow down disease progression and improve patients' quality of life.We have established a stable model of rheumatoid arthritis, which is suitable for the study of preclinical rheumatoid arthritis drugs and the evaluation of new drugs.
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Disease name | Model name | Animal species |
Rheumatoid arthritis | Collagen antibody induced arthritis (CAIA) model | mouse |
Type II collagen induced rheumatoid arthritis model | mouse, rat | |
Adjuvant induced rheumatoid arthritis model | rat | |
Yeast polysaccharide A (ZIA) induced rheumatoid arthritis model | mouse | |
Non human primate spontaneous rheumatoid arthritis model | Non-human primates |
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NHP spontaneous rheumatoid arthritis model
