Key Model for Alzheimer's Drug Development
Alzheimer's disease, or dementia, refers to a persistent disorder of higher neurological activity, which simply means that memory, thinking, analytical judgment, visuospatial recognition, and mood are impaired in the absence of conscious impairment.We have established a stable model of Alzheimer's disease, which is suitable for preclinical Alzheimer's disease drug research and new drug evaluation.
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Disease name | Model name | Animal species |
Alzheimer's disease | APP/PS1 transgenic mouse model of Alzheimer's disease | mouse |
5xFAD mouse Alzheimer's disease model | mouse | |
3xTg mouse Alzheimer's disease model | mouse | |
High fat and high cholesterol diet induced Alzheimer's disease model | rabbit | |
Diffuse blood-brain barrier injury model induced by high-fat and high cholesterol feed | rabbit | |
AAV9 hTau induced rat AD model | rat | |
Aluminum chloride+D-galactosamine (D-Gal) - induced Alzheimer's disease model | rat |